Neuroscience Clinical Trials and Research

Neuroscience Trials 

Neuroscience and stroke trials are overseen by Dr. Nils Mueller-Kronast, regional medical director of neurosciences for Tenet’s Florida region. One of his major goals is to assess the outcomes associated with the use of devices and medications intended to restore blood flow in patients experiencing acute ischemic strokes. Time is brain, and every minute in which a large vessel ischemic stroke is untreated, the patient loses 1.9 million neurons. Reducing this timeline is a major focus of the comprehensive stroke center at Palm Beach Health Network.  

Dr. Lloyd Zucker, chief of neurosurgery at Delray Medical Center, leads the neuro-oncology research trials, which include the use of fluorescence-guided surgery for brain tumors. The technology illuminates cancer cells to help identify and remove smaller tumors that could otherwise go undetected. Other neuro-oncology research trials currently underway at Palm Beach Health Network include minimally invasive brain surgery and interstitial laser thermal therapy. 

OCEANIC-STROKE 

Phase 3 program of the Oral factor Eleven A iNhibitor asundexIan as novel anti-thromboti C-STROKE study 

Principal Investigator
Nils Mueller-Kronast, MD 

Sponsor
Bayer AG 

Click here for more information:  https://clinicaltrials.gov/study/NCT05686070  

AL002 

Assessment of Safety and Efficacy of Exablate Blood-Brain Barrier Disruption for the Treatment of Patients with Probable Alzheimer's Disease  

Principal Investigator
Lloyd Zucker, MD 

Sponsor
Insightec  

Click here for more information:  https://www.clinicaltrials.gov/study/NCT03671889 

PD014 

Evaluation of the Safety and Effectiveness of Exablate Ablation of the Pallidothalamic Tract (PTT) for the treatment of Bilateral Motor Complications of Parkinson's Disease (PD) 

Principal Investigator
Arif Dalvi, MD 

Sponsor
Insightec 

Click here for more information https://www.clinicaltrials.gov/study/NCT04728295

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